Too little is known about what happens in the brain when a decision is being taken to make a donation. This intriguing behavior is often assumed as the substrate to social relationship. In the present study, it was used simulated situations in which participants had to decide how to manage money when possibilities for donation were available. EEG signals were recorded while the participants were exposed to two cognitive situations, the Dictator’s Game and the Prisoner’s Dilemma, to simulate money exchange between people. The brain activity was correlated with decision making to donate. Sixty volunteers were accessed and the stimuli were randomly presented. After the presentation of the cognitive test situation, the participants were allocated in two groups for the respective cognitive situation. The results showed statistical differences in the left prefrontal cortex between questions of donation context and not-donation questions. These results suggest that a logic evaluation occurs when there is a reasonably situation to donate. Therefore participants who heard the question related to donation presented a higher activation in the left prefrontal cortex